منابع مشابه
The influence of gestational dietary calcium on serum 1, 25-dihydroxycholecalciferol in sows and their pigs.
Fifteen multiparous sows (three groups of five) were studied during one gestation-lactation cycle to measure the influence of dietary Ca (.5, .8[control], and 1.1%) on 1,25-dihydroxycholecalciferol (1, 25-(OH)2D3) in serum and colostrum of the sows and serum of their pigs. Concentrations of 1,25-(OH)2D3 and Ca, Mg, P, Cu, and Zn were determined on d 15 and 45 of gestation, at parturition, and a...
متن کاملA high-affinity cytosol binding protein for 1 alpha,25-dihydroxycholecalciferol in the uterus of Japanese quail.
Cytosol fractions prepared from the uterine mucosa of egg-laying Japanese Quail were analysed for binding of the metabolites of cholecalciferol. When the uterus was incubated at 37 degrees C with various radioactive metabolites of cholecalciferol, the nuclear fraction incorporated only 1 alpha,25-dihydroxy[3H]cholecalciferol. When the uterus was incubated at 0 degree C with 1 alpha,25-dihydroxy...
متن کاملReceptor - mediated rapid action of 1 a , 25 - dihydroxycholecalciferol : Increase of intracellular cGMP in human skin fibroblasts ( steroid / signal transduction / nongenomic / calcium ) JULIA BARSONY AND STEPHEN
The intracellular cGMP concentration in normal human cultured fibroblasts was increased 2to 3-fold by la,25-dihydroxycholecalciferol [la,25-(OH)2D3] in a dosedependent manner between 0.01 nM and 1 FM. The response was detectable within 1 min, reached a maximum (225% ± 8% of baseline) at 6-8 min, and was no longer detectable at 30 min. The half-maximal effect of la,25-(OH)2D3 was at 1.8 nM, and ...
متن کامل25-Hydroxy- and 1α,25-Dihydroxycholecalciferol Have Greater Potencies than 25-Hydroxy- and 1α,25-Dihydroxyergocalciferol in Modulating Cultured Human and Mouse Osteoblast Activities
Despite differences in the phamacokinetics of 25-hydroxycholecalciferol (25(OH)D3) and 25-hydroxyergocalciferol (25(OH)D2) in man, the effects of these and their 1α-hydroxylated forms (1,25(OH)2D3 and 1,25(OH)2D2) on cellular activity of vitamin D-responsive cells have hardly been compared. We studied differences in the effects of these metabolites on cell number, gene transcription, protein ex...
متن کاملHormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection.
Autophagy is a self-digestion pathway essential for maintaining cellular homeostasis and cell survival and for degrading intracellular pathogens. Human immunodeficiency virus-1 (HIV-1) may utilize autophagy for replication as the autophagy-related protein-7 (ATG-7), microtubule-associated protein 1 light chain 3, ATG-12, and ATG-16L2 are required for productive HIV-1 infection; however, the eff...
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ژورنال
عنوان ژورنال: Eiyo To Shokuryo
سال: 1979
ISSN: 1883-8863
DOI: 10.4327/jsnfs1949.32.147